The case series was published on the 14th of September 2022, in the Saudi Journal of Anaesthesia / Volume 16 / Issue 4 / October-December by the Anaesthesiology team at AIIMS Jodhpur.

The authors of the publication are: Priyanka Sethi, Raksha Vyas, Manbir Kaur, Pradeep Bhatia from the Department of Anaesthesia and Critical Care, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

The study included a cohort of twenty-one patients who received TSE therapy under sedation and pain relief. Out of the 21 patients, four patients were at very high risk for GA and included one case of locally advanced breast cancer, two cases of head & neck (H&N) carcinoma, and one case of chest wall recurrence of oesophageal carcinoma. The high risk was due to medical reasons. All the patients recovered well and no adverse effect was observed.

"We found it safe to perform the TSE therapy without GA. Instead, we used conscious sedation using trans-nasal humidified rapid-insufflation ventilatory exchange (THRIVE) and dexmedetomidine infusion. This result shows that treating advanced H&N cancer patients doesn't necessarily need to be under GA.." - says Dr Manbir Kaur, Department of Anaesthesia and Critical Care, All India Institute of Medical Sciences (AIIMS)

"The finding in this publication is of great importance for us going forward in India as well as the rest of the world. Avoiding GA not only makes the therapy safer and easier to perform but it also makes the therapy, even more cost efficient for both the healthcare system and for the privately paying patients." - says Dr Suhail Mufti the Medical Adviser for ChemoTech

The publication will be found on ChemoTech's website www.chemotech.se/chemotech-publications/ or can be downloaded from: www.saudija.org