Notice to attend an extraordinary general meeting in ExpreS2ion Biotech Holding AB (publ)

The board of directors has, in accordance with the Company's articles of association, resolved that shareholders shall be entitled to exercise their voting rights by postal voting prior to the general meeting. Shareholders may therefore choose to exercise their voting rights at the meeting in person, through a proxy or by postal voting.

Right to participate and notification

The right to participate in the meeting is held by a person who:

1. is recorded in the share register maintained by Euroclear Nordics AB on 23 November 2026; and
2. has notified the Company of his or her intention to participate in the meeting in accordance with the instructions under the section "Notification for participation in person or through a proxy" no later than on 25 November 2026 or has submitted a postal vote in accordance with the instructions under the section "Instructions for postal voting" no later than on 25 November 2026.

Nominee-registered shares
Shareholders whose shares are registered in the name of a nominee must, in order to participate in the extraordinary general meeting and exercise their voting rights, temporarily re-register the shares in their own name in the share register maintained by Euroclear Nordics AB (so-called voting rights registration). The preparation of the general meeting share register as of the record date of 23 November 2026 will take into account voting rights registrations made no later than on 25 November 2026. This means that the shareholder must request that the nominee carries out such voting rights registration well in advance of that date.

Notification for participation in person or through a proxy
Shareholders who wish to participate in the meeting in person or through a proxy shall notify the Company no later than on 25 November 2026 to ExpreS2ion Biotech Holding AB (publ), "EGM 2026”, c/o Mindpark, Rönnowsgatan 8C, 252 25 Helsingborg, attn: Keith Alexander, or by e-mail to investor@expres2ionbio.com. The notification shall include the shareholder's name, address, telephone number (daytime), personal or registration number, shareholding and the number of any proxies/assistants.

A shareholder who does not wish to attend in person and does not wish to exercise his or her voting rights by postal voting may exercise his or her rights at the meeting through a proxy with a written, signed and dated power of attorney. The power of attorney may not be older than one year, unless a longer period of validity (however, no more than five years) has been stated in the power of attorney. If the power of attorney is issued by a legal entity, a copy of the certificate of registration or equivalent authorisation document for the legal entity shall be enclosed. To facilitate admission to the meeting, powers of attorney, certificates of registration and other authorisation documents should be sent either by e-mail to investor@expres2ionbio.com with the reference "EGM 2026" or by post to ExpreS2ion Biotech Holding AB (publ), ”EGM 2026”, c/o Mindpark, Rönnowsgatan 8C, 252 25 Helsingborg, Sweden, attn: Keith Alexander, no later than on 25 November 2026. Please note that notification of participation in the meeting must be made even if the shareholder wishes to exercise his or her voting rights at the meeting through a proxy. A submitted power of attorney does not constitute notification of participation in the meeting. Proxy forms in Swedish and English are available on the Company's website, investor.expres2ionbio.com.

Instructions for postal voting
Shareholders who wish to exercise their voting rights by postal voting shall use the postal voting form and follow the instructions available on the Company's website, investor.expres2ionbio.com. The postal vote must be received by the Company no later than on 25 November 2026. The postal voting form shall be sent to ExpreS2ion Biotech Holding AB (publ), “EGM 2026”, c/o Mindpark, Rönnowsgatan 8C, 252 25 Helsingborg, attn: Keith Alexander, or by e-mail to investor@expres2ionbio.com with the reference "EGM 2026".

If a shareholder submits a postal vote through a proxy, a written and dated power of attorney shall be enclosed with the postal voting form. Proxy forms are available upon request and are also available on the Company's website, investor.expres2ionbio.com. If the shareholder is a legal entity, a certificate of registration or equivalent authorisation document for the legal entity shall be enclosed. Shareholders may not attach special instructions or conditions to the postal vote. If this is done, the entire postal vote is invalid. Further instructions and conditions are set out in the postal voting form.

For questions regarding the meeting or to receive a postal voting form or a proxy form by post, please contact ExpreS2ion Biotech Holding AB (publ), ”EGM 2026”, c/o Mindpark, Rönnowsgatan 8C, 252 25 Helsingborg, attn: Keith Alexander, or by e-mail to investor@expres2ionbio.com.

Proposed agenda

1. Opening of the meeting and election of chairman of the meeting
2. Preparation and approval of the voting list
3. Election of one or two persons to verify the minutes
4. Determination of whether the meeting has been duly convened
5. Approval of the agenda
6. Resolution on (a) amendments of the articles of association and (b) reduction of the share capital
7. Closing of the meeting

Item 6 – Resolution on (a) amendments of the articles of association and (b) reduction of the share capital
Due to the fact that the Company's shares are currently being traded well below the quota value per share, the board of directors proposes that the general meeting resolves on a reduction of the Company's share capital, in order to adjust the size of the share capital to the Company's operations.

In order to enable the reduction of the Company's share capital under item 6(b) below the board of directors proposes that the general meeting resolves to amend § 4 and § 5 of the articles of association as follows, and resolves on a reduction of the Company's share capital and to adjust the limits of the share capital in the articles of association.

The matters under items 6(a)–(b) constitute one proposal and shall be resolved upon by the general meeting as a single resolution. A valid resolution requires the support of shareholders representing at least two-thirds of both the votes cast and the shares represented at the general meeting.

Item 6(a) – Resolution on amendments of the articles of association
§ 4 of the articles of association is proposed to be worded as follows.

Current wording
The share capital shall be not less than SEK 26,880,000 and not more than SEK 107,520,000.

Proposed wording
The share capital shall be not less than SEK 512,200 and not more than SEK 2,048,800.

§ 5 of the articles of association is proposed to be worded as follows.

Current wording
The number of shares shall be not less than 16,800,000 and not more than 67,200,000

Proposed wording
The number of shares shall be not less than 39,400,000 and not more than 157,600,000.

Item 6(b) – Resolution on reduction of the share capital for allocation to unrestricted equity without redemption of shares
The board of directors proposes that the general meeting resolves to reduce the Company's share capital by SEK 62,636,828.487 to SEK 513,093.113. The reduction shall be carried out without redemption of shares. The reduction amount shall be allocated to unrestricted equity. Following the reduction, the Company's share capital will amount to SEK 513,093.113, divided into a total of 39,468,701 shares, each with a quota value of SEK 0.013.

The reduction of the share capital is subject to the approval of the Swedish Companies Registration Office or a general court. Provided that the necessary approval is obtained, the reduction resolution is expected to be implemented in March 2027.

Documents
Proxy forms, postal voting forms and other documents pursuant to the Swedish Companies Act will be available at the Company's office at Mindpark, Rönnowsgatan 8C in Helsingborg and on the Company's website, investor.expres2ionbio.com, no later than two weeks prior to the meeting. The documents will also be sent to shareholders who so request and provide their postal address.

Shareholders' right to request information
Shareholders are reminded of their right to request information from the board of directors and the chief executive officer at the meeting in accordance with Chapter 7, Section 32 of the Swedish Companies Act.

Processing of personal data
For information on how your personal data is processed, please refer to the privacy policy available on Euroclear's website: www.euroclear.com/dam/ESw/Legal/Integritetspolicy-bolagsstammor-svenska.pdf.

N.B. This notice has been prepared in both Swedish and English language versions. In the event of any discrepancies between the versions, the Swedish version shall prevail. 

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Helsingborg in October 2026
ExpreS2ion Biotech Holding AB (publ)
The Board of Directors