The poster, authored and presented by Keith Miller, focuses on recent advances in HER2 calibrators (i.e., reference material containing a precisely known amount of HER2, enabling standardisation and comparability between laboratories) as well as novel slide-based technologies for HER2 labelling, developed through collaborative efforts between the teams in the United States and in Sweden. The initiative was driven by Keith who identified the work as highly relevant to the pathology community and of significant interest to laboratories seeking to further improve their immunohistochemistry (IHC) services.

The inclusion of this work at one of the UK and Ireland’s leading pathology meetings underscores the growing international interest and market pull for standardised, high-quality solutions in HER2 testing. The same can be applied to companion diagnostics such as PD-L1 and Oestrogen Receptor

”My aim with this poster was to showcase the important and complementary work being carried out on both sides of the Atlantic. There is clear demand within the pathology community for robust IHC calibration tools and improvements in IHC labelling for critical companion diagnostics, such as those for HER2. These developments are absolutely essential, if IHC testing centres are to meet the ever-increasing standards required for patient care,”says Keith Miller, Honorary Associate Professor at the Research Department of Pathology, UCL Cancer Institute, London and honorary member of The Pathological Society of Great Britain & Ireland.

Miller, who spent four decades working in IHC, was the lead of the UK National External Quality Assessment Scheme for Immunocytochemistry and In-Situ Hybridisation. He was also founder of UCL-Advanced Diagnostics, a UK reference centre laboratory for IHC that is now under the Health Service Laboratories in London.

The poster provides an update on ongoing developments and serves to inform pathologists, laboratory managers and decision-makers about technologies that are already available, as well as innovations expected to reach the market in the near future.

The poster is available on Lumito’s website, here.