• Vicore has today been informed that Sanofi has committed to subscribe for shares in the ongoing rights issue corresponding to a total of approximately USD 10.0 million (approximately SEK 102.0 million).
• Vicore recently initiated the Phase 2b ASPIRE trial investigating the disease-modifying potential of buloxibutid in IPF.

Stockholm, September 30, 2024 – Vicore Pharma Holding AB (STO: VICO), a clinical-stage biopharmaceutical company unlocking the potential of a novel class of drug candidates, angiotensin II type 2 receptor agonists (ATRAGs), today announces an investment from Sanofi in Vicore through a commitment to subscribe for shares in the ongoing rights issue corresponding to a total of approximately USD 10.0 million (approximately SEK 102.0 million). The commitment entails a subscription of approximately USD 9.6 million (approximately SEK 98.0 million) through exercise of purchased subscription rights and a subscription of approximately USD 0.4 million (approximately SEK 4.0 million) without the use of subscription rights.

“We are delighted to welcome Sanofi, one of the world’s leading biopharmaceutical companies, as an investor in Vicore as we initiate late-stage development of buloxibutid,” said Ahmed Mousa, Chief Executive Officer of Vicore. “This investment supports our belief in the potential of buloxibutid as a transformative therapy for patients suffering from IPF.”

As any allocation to the investors who entered into guarantee commitments shall only be made up to the number of shares corresponding to the committed amount before the announcement of the rights issue (amounting to approximately MSEK 626, or approximately 80.0 percent of the rights issue), this additional subscription undertaking does not entail an increase in the percentage to which the rights issue is covered by subscription undertakings, subscription intentions and guarantee commitments.
 
For further information, please contact:
Megan Richards, VP of IR, Communications, and Portfolio Strategy, tel: +1 978 269-4372, megan.richards@vicorepharma.com   
Hans Jeppsson, CFO, tel: +46 70 553 14 65, hans.jeppsson@vicorepharma.com
 
This information was submitted for publication on September 30, 2024, at 19:05 CEST.

About Vicore Pharma Holding AB  
Vicore is a clinical-stage pharmaceutical company unlocking the potential of a new class of drugs with disease-modifying potential. The company is advancing a portfolio of therapies in respiratory and fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). Buloxibutid (C21) is a first-in-class orally available small molecule angiotensin II type 2 receptor agonist (ATRAG) being investigated in a global Phase 2b trial in IPF. Almee™ is an investigational digital therapeutic in clinical development that is based on cognitive behavioral therapy and created to address the psychological impact of living with pulmonary fibrosis. Almee has received Breakthrough Device Designation from the FDA, which the Company believes reflects its potential to have transformative impact. Using its expertise in ATRAG chemistry and biology, Vicore is further developing its pipeline with several new therapies across additional indications. The company’s shares are listed on Nasdaq Stockholm’s main market (VICO). www.vicorepharma.com
 
About the Phase 2b ASPIRE Trial
ASPIRE is a global 52-week Phase 2b, randomized, double-blind, placebo-controlled, parallel-group clinical trial designed to assess the efficacy and safety of buloxibutid in IPF patients who are either untreated or receiving background nintedanib standard of care. Participants will be randomized to receive one of two doses of buloxibutid (100 mg or 50 mg taken orally twice daily) or placebo. The primary endpoint is change from baseline in forced vital capacity (FVC), the registrational endpoint for IPF. Secondary endpoints include safety, tolerability, and the proportion of patients with disease progression over the trial period. The trial is expected to enroll 270 patients from over 90 sites across 14 countries, including the United States.
 
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The release, announcement or distribution of this press release may, in certain jurisdictions, be subject to restrictions. The recipients of this press release in jurisdictions where this press release has been published or distributed shall inform themselves of and follow such legal restrictions. The recipient of this press release is responsible for using this press release, and the information contained herein, in accordance with applicable rules in each jurisdiction. This press release does not constitute an offer, or a solicitation of any offer, to buy or subscribe for any securities in Vicore in any jurisdiction, neither from Vicore nor from someone else.
This press release is not a prospectus for the purposes of Regulation (EU) 2017/1129 of the European Parliament and of the Council of 14 June 2017 (the “Prospectus Regulation”) and has not been approved by any regulatory authority in any jurisdiction. A prospectus, prepared in accordance with the simplified disclosure regime for secondary issuances as set forth in the Prospectus Regulation, regarding the Rights Issue described in this press release will be prepared and published by the Company prior to the commencing of the subscription period.
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