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| 2025-02-06 | 08:30 | Bokslutskommuniké 2024 |
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Beskrivning
| Land | Danmark |
|---|---|
| Lista | First North Stockholm |
| Sektor | Hälsovård |
| Industri | Bioteknik |
Hørsholm, Denmark, 24 June 2024 - ExpreS2ion Biotech Holding AB's affiliate ExpreS2ion Biotechnologies ApS ("ExpreS2ion") today announces that the company presented a poster on the use of glycoengineered Drosophila S2 cells for production of highly immunogenic antigens, at the European Society for Animal Cell Technology (ESACT) bi-annual meeting, taking place 23-26 June 2024, in Edinburgh, Scotland.
Modified recombinant antigens with high-mannose or xylosylated N-glycans produced significantly higher antibody titers in immunized mice compared to antigens with S2 wildtype N-glycans.
Although presenting antigens on virus-like particles substantially enhances immunogenicity, a similar effect can be achieved through glycomodification of the soluble antigen.
Both approaches resulted in high antibody titers and their neutralizing capabilities were shown in the virus neutralisation assay for high-mannose antigen.
A copy of the poster can be found at the company webpage www.expres2ionbio.com/events-list/.
For further information about ExpreS2ion, please go to our webpage www.expreS2ionbio.com, or contact us at info@expreS2ionbio.com.