The extended lease includes ISAB's new in vivo module for aerosol exposures to guinea pigs. Guinea pigs are a highly relevant test subjects for inhalation studies. Human and guinea pigs share many similarities in lung anatomy, physiology, pharmacology, particularly airway autonomic control and response to allergens.

The new module employs ISAB's unique one-animal-at-a-time precision dosing method - with single animals being gently dosed through a controlled exposure, generating high-precision data and reducing the need for large numbers of test animals. The guinea pig module is attracting interest from several other customers.

The extended lease is between ISAB and IMM Associate Professor Mikael Adner, Head of the Unit for Experimental Asthma and Allergy Research, a leading expert in pulmonary research and the author of over 100 peer-reviewed papers. Assoc Professor Adner: "We have recently developed a unique guinea pig asthma model where we use relevant allergens and exposure through the airways. With the PreciseInhale[®] we will be able to deliver aerosol with even lung distribution that also reaches the peripheral parts. This will be an important tool in our asthma research. "

ISAB CEO Manoush Masarrat: "Karolinska Institutet is a much-valued, long-term customer and we are pleased to continue our agreement with them. The fact that customers of this calibre keep returning speaks clearly to the exceptional value and precision of our tools."