Key highlights

• United States: DKK 9,829 million (+8%; +11% CER)
• Europe: DKK 4,628 million (+9%; +11% CER)
• International Markets: DKK 4,991 million (-4%; +2% CER)

• Rexulti[®]/Rxulti[®]: DKK 4,525 million (+16%; +20% CER)
• Brintellix[®]/Trintellix[®]: DKK 4,324 million (+1%; +5% CER)
• Abilify Maintena[®]/Asimtufii: DKK 3,187 million (+8%; +10% CER)
• Vyepti[®]: DKK 1,697 million (+69%; +74% CER)

Adjusted EBITDA[2] increased to DKK 5,652 million (+17%; +7% CER) and adjusted EBITDA margin reached 28.4% equivalent to an increase of 2.0 percentage points. Adjusted earnings per share (EPS) reached DKK 4.22 equivalent to an increase of 13%.

In connection with the corporate release, Lundbeck's President and CEO, Charl van Zyl said:

"I am pleased to announce our record results for the year. Lundbeck has presented sustainable growth and is already showing results of the successful R&D transformation. We are currently in the process of strengthening Lundbeck's position as a focused innovator to ensure a sustainable long-term future for our products, innovation, R&D and profitability. Encouraging results are already seen from the AMULET PoC trial in the treatment of Multiple System Atrophy."

In line with our dividend policy, it is proposed to pay-out a dividend of DKK 0.70 per share or DKK 697 million which is an increase of 21% compared to 2022.
 

Key figures

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DKK FY FY Change Change Q4 Q4 2022 Change Change
million 2023 2022 (CER)[1] 2023 (CER)[1]
Revenue 19,912 18,246 9% 8% 4,978 4,680 6% 6%
EBITDA 5,207 4,663 12% 0% 744 910 (18%) (31%)
Adjusted 5,652 4,823 17% 7% 793 1,118 (29%) (38%)
EBITDA
EPS (DKK) 2.31 1.93 20% 0.14 0.31 (55%)
Adjusted 4.22 3.74 13% 0.58 0.87 (33%)
EPS (DKK)

Recent events

On 31 January 2024, Lundbeck announced results of the AMULET PoC trial, a randomized, double-blind, placebo-controlled exploratory proof-of-concept trial. The trial included 61 MSA patients randomized 2:1 (40 on Lu AF82422 versus 21 on placebo) and treated for 48-72 weeks. The primary endpoint in the trial measured slowing of progression of MSA as measured by Unified Multiple System Atrophy Rating Scale (UMSARS) Total Score Part I and II, while the key secondary endpoint was Modified UMSARS Part I. The primary statistical approach consisted of a Bayesian slope analysis. In addition, the trial included several other clinical outcome measures and biomarkers. While the trial did not reach statistical significance on its primary endpoint, a trend towards slowing MSA disease progression was observed in the group exposed to Lu AF82422 compared to the placebo group, and additional signals of efficacy were observed across other clinical and biomarker endpoints. Lu AF82422 was generally well tolerated. Lundbeck plans to initiate a phase III study, following further dialogue with health authorities.

On 30 November 2023, Lundbeck hosted an R&D event in London to update analysts and investors on its transformed R&D pipeline for future growth. The event showcased key pipeline programs and highlighted the company's strategic focus on innovation and life cycle management activities for sustained commercial success.

Financial guidance 2024

For the financial guidance 2024 and going forward, Lundbeck will focus on revenue and adjusted EBITDA at constant exchange rates (CER), instead of revenue and adjusted EBITDA at reported rates, to provide a more focused view of the underlying operational performance.

For 2024, revenue growth is expected to be 7% to 10% at CER when compared to revenue of the prior year excluding the effect from hedging. The growth reflects the continued and sustainable growth driven mainly by the strategic brands.

Lundbeck expects Adjusted EBITDA growth to be 10% to 16% at CER when compared to adjusted EBITDA of the prior year excluding effects from hedging, driven by the growth in revenue. The growth is partially offset by higher R&D investments and higher sales distribution costs due to Vyepti[®] and Rexulti[®] sales activities. Further details are available in section 2.8 Outlook.

[1] Constant Exchange Rates (CER) previously denominated Local Currency (LC). Change at CER does not include effects from hedging.

[2] EBITDA refers to Earnings Before Interest, Taxes, Depreciation and Amortization. Adjusted EBITDA is defined as EBITDA adjusted by certain items, for details see section 4 Notes, note 1 Adjusted EBITDA.