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Beskrivning
| Land | Danmark |
|---|---|
| Lista | First North Denmark |
| Sektor | Hälsovård |
| Industri | Läkemedel & Handel |
STENOCARE A/S
NASDAQ FIRST NORTH GROWTH MARKET, DENMARK
TICKER: STENO
STENOCARE A/S ("Stenocare") reaches an important milestone with ASTRUM 10-10, which is now ready for sale to Norwegian patients. The innovative and patented medical cannabis oil product, ASTRUM 10-10, has the potential to improve uptake in the blood and thereby enhance the efficacy of the treatment.
Stenocare announced on December 2, 2024, that the new innovative medical cannabis oil product, named Astrum 10-10, has been approved for sale in Norway. At the end of December, the first shipment of this product arrived in Norway and is ready for patients' treatment. Officially named 'Astrum 10-10 Oil Stenocare,' the product contains 10 mg/ml THC and 10 mg/ml CBD in a 30 ml bottle.
The Stenocare Astrum product is based on cutting-edge oil technology designed to enhance the bioavailability of cannabinoids in the patient's bloodstream. This innovation addresses a well-known challenge in medicine dosing by ensuring consistent uptake of active ingredients into the blood. With the Astrum product, Stenocare has successfully completed a pharmacokinetic (PK) study in dogs, documenting two critical parameters in the lymphatic system that can significantly improve bioavailability:
Parameter 1 - Uptake in the Blood: According to the pharmacokinetic (PK) study in dogs, Astrum improves blood uptake by a factor of 2.6 compared to a reference MCT-oil product on the market. Low and inconsistent uptake of drugs in the blood across patients is a well-known challenge in the pharmaceutical industry, affecting most medications. This challenge also applies to medical cannabis. When patients use traditional MCT-oil-based medical cannabis, the metabolism often reduces the uptake of cannabinoids in the body. As a result, a highly variable and often limited amount of active ingredients (i.e., cannabinoids) reaches the patient with a therapeutic effect. This creates difficulties in prescribing a consistent dosage to patients. Additionally, blood uptake varies significantly from one individual to another due to biological differences. The new Astrum product helps mitigate these challenges by offering enhanced bioavailability.
Parameter 2 - Time to Maximum Effect: According to the PK- study in dogs, the Stenocare Astrum product reduces the time from dosing to maximum effect from 2-4 hours to just 1 hour, providing a more consistent experience for patients. Predictability of uptake and time to maximum effect is crucial when doctors prescribe medical cannabis and when patients use it to treat their symptoms. Time to maximum effect refers to the duration it takes for the medication to reach its highest concentration in the blood after administration. Achieving this maximum effect as quickly as possible is important to help patients manage their symptoms effectively.