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Beskrivning

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IndustriBioteknik
Ultimovacs är ett norskt läkemedelsbolag. Bolagets affärsinriktning är att utveckla immunoterapier mot diverse cancertillstånd. Forskning och utveckling utgår ifrån egenbaserad teknologisk plattform, där produkterna huvudsakligen vidareutvecklas som vaccin. Störst närvaro återfinns inom Europa och Nordamerika. Bolaget grundades under 2011 och har sitt huvudkontor i Oslo, Norge.
2024-04-24 16:14:55
NON-REGULATORY PRESS RELEASE

Oslo, April 24, 2024: Ultimovacs ASA ("Ultimovacs") (OSE ULTI), a clinical-stage
biotechnology company developing immunotherapeutic cancer vaccines, today
announces that the data from the Phase II clinical trial INITIUM (NCT04382664
(https://clinicaltrials.gov/study/NCT04382664?term=ultimovacs&rank=2)), will be
presented in a poster session at the 2024 ASCO Annual Meeting, taking place May
31 - June 4, 2024, in Chicago, IL & Online.

INITIUM is an Ultimovacs-sponsored randomized, comparative, multicenter Phase II
trial evaluating the company's therapeutic cancer vaccine candidate UV1 in
combination with the checkpoint inhibitors ipilimumab and nivolumab as first-
line treatment in unresectable or metastatic malignant melanoma. The trial was
conducted at 39 hospitals across the U.S., U.K., Belgium, and Norway, and 156
patients were enrolled between June 2020 and July 2022.

The poster presentation features key findings and analyses after a minimum 18-
month follow-up of the patients in the trial.

Presentation Details:

Abstract Number: LBA9519
Abstract Title: Ipilimumab and nivolumab plus UV1, an anticancer vaccination
against telomerase, in advanced melanoma.

Session Title: Poster Session - Melanoma/Skin Cancers
Poster Board: 303
Date and Time: June 1, 2024 1:30 PM - 4:30 PM (CT)
Presenter: Paul Lorigan, Professor of Medical Oncology at the University of
Manchester and Investigator in the INITIUM study

Late-Breaking Abstracts are under embargo and will be released at 7:00 AM
(CT)/8:00 AM (ET) on the day of the presentation.

==ENDS==

About Ultimovacs
Ultimovacs is a clinical-stage biotechnology leader in novel immunotherapeutic
cancer vaccines. The lead cancer vaccine candidate UV1 is an off-the-shelf
vaccine directed against human telomerase (hTERT), an antigen present in 85-90%
of cancers in all stages of tumor growth. A broad clinical program, with Phase
II trials in five cancer indications enrolling more than 670 patients, aims to
investigate UV1's impact in combination with other immunotherapies in multiple
cancer types. UV1 is a patented technology owned by Ultimovacs. In addition,
Ultimovacs holds all rights to the proprietary TET technology platform for any
possible future use of formulations in various solid tumor indications.

The Company is listed on the Euronext Oslo Stock Exchange (ULTI).

For further information, please contact:

Carlos de Sousa, CEO
Email: carlos.desousa@ultimovacs.com (mailto:carlos.desousa@ultimovacs.com)
Phone: +47 908 92507

Anne Worsøe, Head of Investor Relations
Email: anne.worsoe@ultimovacs.com (mailto:anne.worsoe@ultimovacs.com)
Phone: +47 90686815

This stock exchange announcement was published by Anne Worsøe, Head of Investor
Relations at Ultimovacs ASA, on April 24, 2024, at 16:15 CET.