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2025-11-05 07:30 Kvartalsrapport 2025-Q3
2025-08-06 07:30 Kvartalsrapport 2025-Q2
2025-05-07 07:30 Kvartalsrapport 2025-Q1
2025-03-28 - X-dag halvårsutdelning NOVO B 7.9
2025-03-27 - Årsstämma
2025-02-05 - Bokslutskommuniké 2024
2024-11-06 - Kvartalsrapport 2024-Q3
2024-08-15 - X-dag halvårsutdelning NOVO B 3.5
2024-08-07 - Kvartalsrapport 2024-Q2
2024-05-02 - Kvartalsrapport 2024-Q1
2024-03-22 - X-dag halvårsutdelning NOVO B 6.4
2024-03-21 - Årsstämma
2024-01-31 - Bokslutskommuniké 2023
2023-11-02 - Kvartalsrapport 2023-Q3
2023-09-13 - Split NOVO B 1:2
2023-08-18 - X-dag halvårsutdelning NOVO B 6
2023-08-10 - Kvartalsrapport 2023-Q2
2023-05-04 - Kvartalsrapport 2023-Q1
2023-03-24 - X-dag halvårsutdelning NOVO B 8.15
2023-03-23 - Årsstämma
2023-02-01 - Bokslutskommuniké 2022
2022-11-02 - Kvartalsrapport 2022-Q3
2022-08-12 - X-dag halvårsutdelning NOVO B 4.25
2022-08-04 - Kvartalsrapport 2022-Q2
2022-05-04 - Kvartalsrapport 2022-Q1
2022-03-25 - X-dag halvårsutdelning NOVO B 6.9
2022-03-24 - Årsstämma
2022-02-02 - Bokslutskommuniké 2021
2021-11-03 - Kvartalsrapport 2021-Q3
2021-08-16 - X-dag halvårsutdelning NOVO B 3.5
2021-08-05 - Kvartalsrapport 2021-Q2
2021-05-05 - Kvartalsrapport 2021-Q1
2021-03-26 - X-dag halvårsutdelning NOVO B 5.85
2021-03-25 - Årsstämma
2021-02-03 - Bokslutskommuniké 2020
2020-10-30 - Kvartalsrapport 2020-Q3
2020-08-14 - X-dag halvårsutdelning NOVO B 3.25
2020-08-06 - Kvartalsrapport 2020-Q2
2020-05-06 - Kvartalsrapport 2020-Q1
2020-03-27 - X-dag halvårsutdelning NOVO B 5.35
2020-03-26 - Årsstämma
2020-02-05 - Bokslutskommuniké 2019
2019-11-01 - Kvartalsrapport 2019-Q3
2019-08-21 - Kvartalsrapport 2019-Q2
2019-08-16 - X-dag halvårsutdelning NOVO B 3
2019-05-03 - Kvartalsrapport 2019-Q1
2019-03-22 - X-dag halvårsutdelning NOVO B 5.15
2019-03-21 - Årsstämma
2019-02-01 - Bokslutskommuniké 2018
2018-08-18 - X-dag halvårsutdelning NOVO B 3
2018-08-17 - X-dag halvårsutdelning NOVO B 3
2018-08-08 - Kvartalsrapport 2018-Q2
2018-05-02 - Kvartalsrapport 2018-Q1
2018-03-23 - X-dag halvårsutdelning NOVO B 4.85
2018-03-22 - Årsstämma
2018-02-01 - Bokslutskommuniké 2017
2017-11-01 - Kvartalsrapport 2017-Q3
2017-08-18 - X-dag halvårsutdelning NOVO B 3
2017-08-09 - Kvartalsrapport 2017-Q2
2017-05-03 - Kvartalsrapport 2017-Q1
2017-03-24 - X-dag ordinarie utdelning NOVO B 4.60 DKK
2017-03-23 - Årsstämma
2017-02-02 - Bokslutskommuniké 2016
2016-10-28 - Kvartalsrapport 2016-Q3
2016-08-12 - X-dag halvårsutdelning NOVO B 3
2016-08-05 - Kvartalsrapport 2016-Q2
2016-04-29 - Kvartalsrapport 2016-Q1
2016-03-21 - X-dag halvårsutdelning NOVO B 6.4
2016-03-18 - Årsstämma
2016-02-03 - Bokslutskommuniké 2015
2015-10-29 - Kvartalsrapport 2015-Q3
2015-08-06 - Kvartalsrapport 2015-Q2
2015-04-30 - Kvartalsrapport 2015-Q1
2015-03-20 - X-dag ordinarie utdelning NOVO B 5.00 DKK
2015-03-19 - Årsstämma
2015-01-30 - Bokslutskommuniké 2014
2014-10-30 - Kvartalsrapport 2014-Q3
2014-08-07 - Kvartalsrapport 2014-Q2
2014-05-01 - Kvartalsrapport 2014-Q1
2014-03-21 - X-dag ordinarie utdelning NOVO B 4.50 DKK
2014-03-20 - Årsstämma
2014-02-03 - Bokslutskommuniké 2013
2014-01-02 - Split NOVO B 1:5
2013-10-31 - Kvartalsrapport 2013-Q3
2013-08-08 - Kvartalsrapport 2013-Q2
2013-05-01 - Kvartalsrapport 2013-Q1
2013-03-21 - X-dag ordinarie utdelning NOVO B 18.00 DKK
2013-03-20 - Årsstämma
2013-02-04 - Bokslutskommuniké 2012
2012-10-31 - Kvartalsrapport 2012-Q3
2012-08-09 - Kvartalsrapport 2012-Q2
2012-04-27 - Kvartalsrapport 2012-Q1
2012-03-22 - X-dag ordinarie utdelning NOVO B 14.00 DKK
2012-03-21 - Årsstämma
2012-02-02 - Bokslutskommuniké 2011
2011-10-27 - Kvartalsrapport 2011-Q3
2011-08-04 - Kvartalsrapport 2011-Q2
2011-04-28 - Kvartalsrapport 2011-Q1
2011-03-24 - X-dag ordinarie utdelning NOVO B 10.00 DKK
2011-03-23 - Årsstämma
2011-02-02 - Bokslutskommuniké 2010
2010-03-25 - X-dag ordinarie utdelning NOVO B 7.50 DKK
2007-12-03 - Split NOVO B 1:2
2001-04-04 - Split NOVO B 1:5
1997-01-02 - Split NOVO B 1:2

Beskrivning

LandDanmark
ListaLarge Cap Copenhagen
SektorHälsovård
IndustriLäkemedel & Handel
Novo Nordisk är en producent av insulin för diabetesbehandling. Utöver specialistkompetensen inom diabetes producerar bolaget läkemedel för hormonbehandling samt produkter för hemofili och blödningsrubbningar. Produkterna återfinns på en global marknad och säljs under separata varumärken. Bolaget grundades ursprungligen under 1923 och har sitt huvudkontor i Bagsværd, Danmark.
2025-03-29 15:33:58
  • Ozempic® improved maximum walking distance by 13% vs placebo in adults with type 2 diabetes and peripheral artery disease (PAD) in the phase 3 STRIDE trial1.
  • Data were presented at the American College of Cardiology's (ACC) Annual Scientific Session and Expo in Chicago, US, while simultaneously published today in The Lancet2.
  • Approximately 230 million people globally have PAD, a severe form of atherosclerotic cardiovascular disease3, and nearly one in three people with PAD have type 2 diabetes4.

Bagsværd, Denmark, 29 March 2025 – Novo Nordisk today presented the full results from STRIDE, a phase 3b peripheral artery disease (PAD) outcomes trial investigating the effects of once-weekly injectable Ozempic® (semaglutide 1.0 mg) in adults with type 2 diabetes and PAD, at the American College of Cardiology's (ACC) Annual Scientific Session and Expo in Chicago, US1. These new data from the phase 3 trial were featured during a late-breaking clinical trial session at the ACC and simultaneously published today in The Lancet2.

The double-blind, randomised, placebo-controlled STRIDE trial achieved its primary endpoint, with semaglutide 1.0 mg demonstrating a superior and clinically meaningful improvement of 13% in maximum walking distance and a mean treatment difference of 39.9 meters on a steep incline, compared to placebo at week 52. The trial also demonstrated superiority to placebo for all confirmatory secondary outcomes assessed, including pain-free walking distance at week 52, health-related quality of life (Vascular Quality of Life Questionnaire-6) at week 52, and maximum walking distance at week 571.

“Peripheral artery disease (PAD) may cause severe symptoms, physical limitations, and a diminished quality of life, often making even short walks, such as retrieving the mail challenging. In individuals with PAD and diabetes, the disease can be even more severe, affecting small blood vessels and limiting the effectiveness of revascularization procedures and other treatments. Semaglutide 1.0 mg is the first medication in over two decades to show improvements in cardiometabolic and cardiovascular outcomes as well as meaningful improvements in functional capacity and quality of life, which could address a critical unmet need for those with both PAD and type 2 diabetes," said Marc P. Bonaca, MD, Director of Vascular Research, University of Colorado School of Medicine, Lead Investigator of the STRIDE trial. “The significant improvements in walking distance and patient-reported quality of life observed with semaglutide 1.0 mg in the STRIDE trial are promising and represent an important step forward on the path to advancing treatment options for this patient population.”

PAD is a severe form of atherosclerotic cardiovascular disease that is under-screened and underdiagnosed and impacts approximately 230 million people globally3. Type 2 diabetes is one of the leading risk factors for PAD, and nearly one in three people with PAD have type 2 diabetes4. There are limited therapies available to specifically improve functional limitations in PAD, representing a significant unmet need in this population5.

“Novo Nordisk continues to evolve its focus beyond diabetes and obesity towards a broader spectrum of metabolic and cardiovascular health,” said Martin Holst Lange, executive vice president for Development at Novo Nordisk. “These data, alongside other data being presented at ACC, reinforce the comprehensive set of health benefits of semaglutide, making it a strong option for healthcare professionals addressing the spectrum of metabolic and cardiovascular health – and our continued leadership in the space.”

The safety results from the STRIDE trial are consistent with the well-established safety and tolerability profile of once-weekly semaglutide1, supported by long-term safety data with more than 33 million patient-years of exposure6. Serious adverse events (SAEs) were reported in fewer participants in the semaglutide group than in the placebo group (74 [19%] vs 78 [20%]). SAE probably related to treatment occurred in 2 participants (1%) in the semaglutide group and in 2 participants (1%) in the placebo group. SAE possibly related to treatment occurred in 3 (1%) and 4 (1%) participants, respectively. SAEs leading to permanent treatment discontinuation of semaglutide or placebo were less common in the semaglutide group than in the placebo group (11 [3%] vs 13 [3%]). SAEs led to the death of 3 (1%) and 8 (2%) participants in the semaglutide and placebo arms, respectively; however, no SAEs leading to death were treatment-related1.

Based on data from the STRIDE clinical trial, Novo Nordisk submitted a label extension application for Ozempic® to the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA). A decision is anticipated in 2025.

About STRIDE

STRIDE is a double-blind, randomised, placebo-controlled phase 3b clinical trial assessing the benefit of once-weekly injectable semaglutide 1.0 mg, marketed as Ozempic®, on functional capacity. It enrolled 792 participants with type 2 diabetes and symptomatic PAD with walking-induced leg pain. The primary endpoint was maximum walking distance on a constant load treadmill for people treated with semaglutide compared to placebo at week 52. STRIDE is the only dedicated PAD functional outcomes trial with a GLP-1 RA.

About PAD
Lower extremity PAD is a severe form of atherosclerotic cardiovascular disease. The classical symptom is intermittent claudication, associated with limited walking ability and poor health-related quality of life7. Type 2 diabetes is one of the leading risk factors for PAD; nearly one in three people with PAD have type 2 diabetes4. While anti-atherosclerotic therapies and lifestyle changes are recommended, there are no effective therapies to specifically improve functional outcomes in PAD and type 2 diabetes8.

About Ozempic®
Ozempic® (semaglutide) injection 0.25, 0.5 mg, 1.0 mg or 2.0 mg is a once-weekly GLP-1 RA indicated, along with diet and exercise, to improve blood sugar (glucose) in adults with type 2 diabetes mellitus and to reduce the risk of major cardiovascular events such as heart attack, stroke or death in adults with type 2 diabetes mellitus with known heart disease9,10. Ozempic® is currently marketed in 75 countries and 7 million people with type 2 diabetes are currently being treated with Ozempic® worldwide11.

About Novo Nordisk
Novo Nordisk is a leading global healthcare company founded in 1923 and headquartered in Denmark. Our purpose is to drive change to defeat serious chronic diseases built upon our heritage in diabetes. We do so by pioneering scientific breakthroughs, expanding access to our medicines and working to prevent and ultimately cure disease. Novo Nordisk employs about 76,300 people in 80 countries and markets its products in around 170 countries. Novo Nordisk's B shares are listed on Nasdaq Copenhagen (Novo-B). Its ADRs are listed on the New York Stock Exchange (NVO). For more information, visit novonordisk.com, Facebook, Instagram, X, LinkedIn and YouTube.

Contacts for further information

Media: 
Ambre James-Brown
+45 3079 9289
abmo@novonordisk.com

Liz Skrbkova (US)
+1 609 917 0632
lzsk@novonordisk.com

Investors: 
Jacob Martin Wiborg Rode
+45 3075 5956
jrde@novonordisk.com

Ida Schaap Melvold
+45 3077 5649
idmg@novonordisk.com

Sina Meyer
+45 3079 6656
azey@novonordisk.com

Max Ung
+45 3077 6414
mxun@novonordisk.com

Frederik Taylor Pitter
+1 609 613 0568
fptr@novonordisk.com

 

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References
1.   Bonaca M, et al. Oral presentation presented at the American College of Cardiology Congress Scientific Session & Expo 2025; 29–31 March 2025. Presentation 102-09.
2.   The Lancet: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00509-4/fulltext
3.   Gornik HL, et al. Circulation. 2024;149:e1313–e1410.
4.   Thiruvoipati T, et al. World J Diabetes. 2015;6:961–969.
5.   Aronow WS. Arch Med Sci. 2012;8:375–388.
6.   Bonaca MP, et al. Eur Heart J Cardiovasc Pharmacother. 2025;10:728–737.
7.   Novo Nordisk Data on File.
8.   Sillesen H, et al. European Heart Journal. 2021;42:ehab724.2027.
9.   Ozempic® (semaglutide): SmPC. 2025 [online] Available at: https://www.ema.europa.eu/en/documents/product-information/ozempic-epar-product-information_en.pdf Last accessed: March 2025.
10.   Ozempic® (semaglutide) US PI. 2025 [online] Available at: https://www.novo-pi.com/ozempic.pdf Last accessed: March 2025.
11.   Novo Nordisk Data on File. IQVIA Ozempic and Rybelsus patient numbers March 2025.