Right to participate in the Annual General Meeting and notice of participation
Participation at the venue
A shareholder who wishes to participate in the Annual General Meeting at the venue in person or represented by a proxy must (i) be recorded as a shareholder in the share register maintained by Euroclear Sweden AB relating to the circumstances on Monday, 14 April 2025, and (ii) no later than Wednesday, 16 April 2025, give notice by post to Biotage AB (publ), c/o Advokatfirman Vinge, Box 1703, SE-111 87 Stockholm, Sweden or via e-mail to BiotageAGM@vinge.se. When providing such notice, the shareholder shall state name, personal or corporate registration number, address, telephone number and the number of any accompanying assistant(s) (maximum two assistants) as well as information about any proxy.

If a shareholder is represented by proxy, a written, dated proxy for the representative must be issued. A proxy form is available on the company’s website, www.biotage.com. If the proxy is issued by a legal entity, a certificate of registration or equivalent certificate of authority should be enclosed. To facilitate the registration at the Annual General Meeting, the proxy and the certificate of registration or equivalent certificate of authority should be sent to the company as set out above so that it is received no later than Wednesday, 23 April 2025.

Participation by advance voting
A shareholder who wishes to participate in the Annual General Meeting by advance voting must (i) be recorded as a shareholder in the share register maintained by Euroclear Sweden AB relating to the circumstances on Monday, 14 April 2025 and (ii) no later than Wednesday, 16 April 2025, give notice by casting its advance vote in accordance with the instructions below so that the advance vote is received by Biotage no later than on that day.

A shareholder who wishes to participate in the Annual General Meeting at the venue in person or represented by a proxy must give notice thereof in accordance with what is set out under Participation at the venue above. This means that a notification by advance vote is not sufficient for a person who wishes to participate at the venue.

A special form shall be used when advance voting. The advance voting form is available on the company’s website, www.biotage.com. A completed and signed form may be submitted by post to Biotage AB (publ), c/o Advokatfirman Vinge, Box 1703, SE-111 87 Stockholm, Sweden or via e-mail to BiotageAGM@vinge.se. The completed and signed form shall be received by Biotage not later than Wednesday, 16 April 2025. The shareholder may not provide special instructions or conditions in the voting form. If so, the vote (i.e. the advance vote in its entirety) is invalid. Further instructions and conditions are included in the form for advance voting.

If a shareholder votes by proxy, a written and dated proxy shall be enclosed to the advance voting form. A proxy form is available on the company’s website, www.biotage.com. If the shareholder is a legal entity, a certificate of registration or equivalent certificate of authority should be enclosed.

If a shareholder has voted in advance and then attends the Annual General Meeting in person or through a proxy, the advance vote is still valid except to the extent the shareholder participates in a voting procedure at the Annual General Meeting or otherwise withdraws its casted advance vote. If the shareholder chooses to participate in a voting at the Annual General Meeting, the vote cast will replace the advance vote with regard to the relevant item on the agenda.

Nominee registration
To be entitled to participate in the Annual General Meeting, a shareholder whose shares are registered in the name of a nominee through a bank or a securities institution must, in addition to providing notification of participation, register its shares in its own name so that the shareholder is recorded in the share register relating to the circumstances on Monday, 14 April 2025. Such registration may be temporary (so-called voting right registration) and is requested from the nominee in accordance with the nominee’s procedures and in such time in advance as the nominee determines. Voting right registrations completed by the nominee not later than Wednesday, 16 April 2025, are taken into account when preparing the share register.

Right to request information
The shareholders are reminded of their right to, at the Annual General Meeting, obtain information from the Board of Directors and CEO in accordance with chapter 7, section 32 of the Swedish Companies Act. Shareholders who wish to submit questions in advance may do so by sending post to Biotage AB (publ), c/o Advokatfirman Vinge, Box 1703, SE-111 87 Stockholm, Sweden or via e-mail to BiotageAGM@vinge.se.

Number of shares and votes
As of the date of this notice there are a total of 80,049,272 ordinary shares in the company that entitle to one vote per share at the Annual General Meeting. Further, the company holds 904,863 own class C shares, which entitle to one tenth of a vote per share and which cannot be represented at the Annual General Meeting. The class C shares do not entitle to dividends. Thus, there are a total of 80,954,135 shares and 80,139,758.3 votes in the company, of which 80,049,272 shares and votes can be represented at the Annual General Meeting.

Proposed Agenda
1.       Opening of the Annual General Meeting.
2.       Election of the Chairman of the Annual General Meeting.
3.       Preparation and approval of the voting list.
4.       Approval of the agenda.
5.       Election of two persons to approve the minutes.
6.       Determination whether the Annual General Meeting has been duly convened.
7.       Presentation by the CEO.
8.       Presentation of the annual report and the auditor’s report, as well as the consolidated accounts and the auditor’s report on the consolidated accounts.
9.       Resolutions on approval of the income statement and the balance sheet, and the consolidated income statement and the consolidated balance sheet.
10.   Resolution on allocation of the company’s profit or loss pursuant to the approved balance sheet.
11.   Resolution on discharge from liability for the board members and the CEO.
12.   Resolution on the number of board members to be elected by the Annual General Meeting, and the number of auditors.
13.   Resolution on the fees payable to the Board of Directors and the auditors.
14.   Election of board members and Chairman of the Board of Directors.
15.   Election of auditors.
16.   Resolution on the Nomination Committee.
17.   Presentation of the Board of Directors’ remuneration report for approval.
18.   Resolution on adoption of long-term incentive plan (LTIP).
19.   Resolution on authorization for the Board of Directors to issue shares.
            a) Main proposal.
            b) Alternative proposal.
20.   Closing of the Annual General Meeting.
 
Proposals of the Nomination Committee

Items 2 and 12 to 15 – Election of Chairman of the Annual General Meeting, resolution on the number of board members to be elected by the Annual General Meeting and the number of auditors, resolution on fees payable to the Board of Directors and auditors and election of board members and Chairman of the Board of Directors and election of auditors
The Nomination Committee of Biotage AB (publ), consisting of Kugan Sathiyanandarajah, Chairman (appointed by Gamma Biosciences), Patrik Jönsson (appointed by SEB Funds AB), Kristian Åkesson (appointed by Carnegie Fonder) and Kieran Murphy (Chairman of the Board of Directors and adjunct member of the Nomination Committee) proposes the following:
- Dain Hård Nevonen, member of the Swedish Bar Association, from Advokatfirman Vinge, or the person appointed by the Nomination Committee if he has an impediment to attend, shall be elected Chairman of the Annual General Meeting.
- Seven board members (with no deputy board members) shall be elected and the number of auditors shall be one registered public accounting firm.
- Fees payable to the auditors for the period up to and including the Annual General Meeting to be held in 2026 shall be paid against approved account.
- Election of the auditing firm Öhrlings PricewaterhouseCoopers AB (“PwC”), as the company’s auditor for the period until the end of the Annual General Meeting to be held in 2026. Camilla Samuelsson is proposed by PwC as auditor in charge if they are elected. The proposal is in accordance with the audit committee’s recommendation.
 
The Nomination Committee proposes an increased fee for the ordinary members of the Board of Directors and the Chairman and an unchanged fee to the members of the Audit Committee and the Compensation Committee: A fixed fee payable to the Board of Directors (fees for 2024 in brackets), including fees for work in respect of committees, of SEK 3,530,000 (2,895,000) shall be determined for the period up to and including the Annual General Meeting to be held in 2026 to be distributed as follows: The Chairman shall receive SEK 950,000 (850,000) and each of the other board members elected by the Annual General Meeting who are not employed by the company shall receive SEK 360,000 (325,000). Furthermore, a fee shall be paid to the members of the Audit Committee of an aggregate of not more than SEK 270,000 (270,000), of which the Chairman shall receive SEK 160,000 (160,000) and the other two members SEK 55,000 (55,000) each and a fee shall be paid to the members of the Compensation Committee of an aggregate of not more than SEK 150,000 (150,000), of which the Chairman shall receive SEK 80,000 (80,000) and the other two members SEK 35,000 (35,000) each.
 
The Nomination Committee proposes re-election, for the period until the end of the Annual General Meeting to be held in 2026, of the currently elected members of the Board of Directors Kieran Murphy, Torben Jørgensen, Åsa Hedin, Peter Ehrenheim, Mark Bradley, Karen Lykke Sørensen and Kugan Sathiyanandarajah. Kieran Murphy is proposed to be elected as Chairman of the Board of Directors.
 
A presentation in relation to the individuals proposed by the Nomination Committee for re-election is available at www.biotage.com.

Item 16 – Resolution on the Nomination Committee
The Nomination Committee proposes that the Annual General Meeting resolves to adopt an unchanged instruction for the Nomination Committee, compared to last year, in accordance with the following:
The company shall have a Nomination Committee consisting of three ordinary members. The members should be one representative of each of the three largest shareholders in the company with regard to the number of votes held who wish to appoint such representatives. The Chairman of the Board of Directors of the company shall be an adjunct member of the Nomination Committee and shall convene the first meeting of the Nomination Committee. The Nomination Committee shall perform the duty of the Nomination Committee in accordance with the Swedish Corporate Governance Code. The Nomination Committee’s term of office shall extend until a new Nomination Committee is appointed.

The Nomination Committee shall be composed based on shareholder statistics from Euroclear Sweden AB as of the last banking day in August and other reliable shareholder information which has been provided to the company at such time. When determining who are the three largest shareholders with regard to the number of votes held, a group of shareholders shall be considered as one owner if they (i) have been organized as a group in the Euroclear-system or (ii) have made public and notified the company that they have made a written agreement to take – through the coordinated exercise of voting rights – a common long-term view on the management of the company. The Nomination Committee shall appoint one of the members, who is not the Chairman of the Board of Directors, as Chairman of the Nomination Committee. The Chairman of the Nomination Committee shall, if the Nomination Committee does not resolve otherwise, be the member that represents the largest shareholder with regard to the number of votes held. The names of the representatives and the names of the shareholders they represent shall be announced as soon as they have been appointed.

If, during the term of office of the Nomination Committee, one or more shareholders having appointed a representative to the Nomination Committee no longer is among the three largest shareholders with regard to the number of votes held, representatives appointed by these shareholders shall resign and the shareholder or shareholders who then are among the three largest shareholders with regard to the number of votes held, may appoint their representatives. In the event that a member leaves the Nomination Committee before its term of office is completed, the shareholder who appointed the member shall appoint a new member. If this shareholder is no longer one of the three largest shareholders with regard to the number of votes held, a new member is appointed according to the above procedure. Unless there are special circumstances, no changes shall be made in the composition of the Nomination Committee if there are only marginal changes in the number of votes held or if the change occurs later than three months before the Annual General Meeting. A shareholder that has become one of the three largest shareholders, with regard to the number of votes held, due to a more significant change in the number of votes held later than three months before the Annual General Meeting shall, however, be entitled to appoint a representative who shall be invited to participate in the Nomination Committee’s work as a co-opted member. A shareholder who has appointed a representative as member of the Nomination Committee has the right to dismiss such member and appoint a new representative as member of the Nomination Committee. Changes in the composition of the Nomination Committee shall be announced as soon as they have occurred.

Proposals of the Board of Directors
Item 10 – Resolution on the appropriation of earnings
The Board of Directors proposes a dividend of SEK 1.65 per share. Record date for dividend is proposed to be Monday, 28 April 2025. Payment of dividend is thus estimated to be effectuated by Euroclear Sweden AB on Friday, 2 May 2025.

Item 18 – Resolution on adoption of long-term incentive plan (LTIP)
The Board of Directors proposes that the Annual General Meeting resolves to adopt a long-term incentive programme based on performance-based share rights for employees in the Biotage group (“LTIP 2025”) in accordance with this item 18.

Proposal to adopt LTIP 2025 and hedging arrangements

The programme in brief
LTIP 2025 is proposed to include the CEO, executive management, extended management and other key employees, meaning that a maximum of approximately 19 individuals within the Biotage group will be able to participate. Participants will be given the opportunity to receive ordinary shares free of charge within the framework of LTIP 2025, so-called “Performance Shares”, in accordance with the conditions set out below.
Within the framework of LTIP 2025, the company will allot participants rights to Performance Shares which means that, subject to certain conditions being met, the right to receive a Performance Share free of charge (“Share Rights”).

Terms and conditions
A Share Right may be exercised provided that the participant, with certain exceptions, from the start date of the LTIP 2025 for each participant, up until and including the date three years thereafter (the “Vesting Period”), is still employed by the Biotage group. The last date for the start of the LTIP 2025 shall be the day before the Annual General Meeting of Biotage in 2026. In addition to the requirement for the participant’s continued employment according to the above, the final number of Performance Shares that each participant is entitled to receive shall also be conditional upon the following performance conditions:
(i)        25 per cent of the Performance Shares related to the total shareholder return (the return to shareholders through an increased share price and reinvestments of any dividends during the Vesting Period) on the company’s ordinary shares during the Vesting Period (“Performance Condition 1”),
(ii)       25 per cent of the Performance Shares related to an average adjusted EBITDA-margin during the period from and including the financial year 2025 and up to and including the financial year 2027 (the “Measurement Period”) (“Performance Condition 2”),[1]
(iii)    25 per cent of the Performance Shares related to average organic sales growth over the Measurement Period (“Performance Condition 3”), and
(iv)    25 per cent of the Performance Shares related to the company’s ESG goal to reduce Biotage’s CO2 footprint[2] over the Measurement Period (“Performance Condition 4”).

Participants will be entitled to 25 per cent of the Performance Shares under Performance Condition 1 if the total shareholder return amounts to or exceeds 33.1 per cent (corresponding to 10 per cent per year) during the Vesting Period. For allotment of Performance Shares under Performance Condition 1, the total shareholder return for the company’s ordinary share must exceed 15.8 per cent (corresponding to 5 per cent per year) during the Vesting Period. In between the percentages, allotment will be made linearly.
Participants will be entitled to 25 per cent of the Performance Shares under Performance Condition 2 if the average adjusted EBITDA-margin amounts to or exceeds 29 per cent during the Measurement Period. For allotment of Performance Shares under Performance Condition 2, the average adjusted EBITDA-margin must exceed 25 per cent during the Measurement Period. In between the percentages, allotment will be made linearly.
Participants will be entitled to 25 per cent of the Performance Shares under Performance Condition 3 if the average organic sales growth amounts to or exceeds 12 per cent during the Measurement Period. For allotment of Performance Shares under Performance Condition 3, the average organic sales growth must exceed 5 per cent during the Measurement Period. In between percentages, allotment will be made linearly.
Finally, participants will be entitled to 25 per cent of the Performance Shares under Performance Condition 4 (the company’s ESG goal) if the reduction of Biotage’s CO2 footprint amounts to or exceeds 20 per cent during the Measurement Period. For allotment of Performance Shares under Performance Condition 4, the reduction of Biotage’s CO2 footprint must exceed 10 per cent during the Measurement Period. In between percentages, allotment will be made linearly.

Share Rights
The Share Rights shall, in addition to what is set out above, be governed by the following terms and conditions:
·       Share Rights are allotted free of charge no later than the day before the Annual General Meeting 2026.
·       Share Rights vest during the Vesting Period.
·       Share Rights may not be transferred or pledged.
·       Each Share Right entitles the participant to receive one Performance Share free of charge after the end of the Vesting Period (with certain exceptions where the Vesting Period may be accelerated) if the participant, with certain exceptions, is still employed by the Biotage group by the end of the Vesting Period.

Preparation of the proposal, design and administration
The Board of Directors, or a special committee set up by the board, shall be responsible for preparing the detailed design and administration of the terms and conditions of LTIP 2025, in accordance with the presented terms and guidelines including provisions on recalculation in the event of an in-between bonus issue, share split, rights issue and/or similar measures. No recalculations will be made in relation to paid dividends. In connection with any recalculations, the Board of Directors shall be entitled to make adjustments to meet specific foreign regulations or market conditions. The Board of Directors may also make other adjustments if significant changes in the Biotage group or in its environment would result in a situation where the adopted terms and conditions of LTIP 2025 no longer serve their purpose.

Allotment of Share Rights
The participants are divided into different categories and, in accordance with the above, the Share Rights under LTIP 2025 may be allotted to the following participants in the different categories:
 

Receiving Performance Shares under LTIP 2025 and hedging arrangements
The Board of Directors has considered different methods for transfer of ordinary shares under LTIP 2025 in order to implement the programme in a cost-effective and flexible manner and has found the most cost-effective alternative to be, in accordance with previously adopted LTIP programs, a structure based on class C shares. As of the date of this notice, the company holds 904,863 own class C shares (the “Treasury Shares”). These Treasury Shares are sufficient to cover delivery under LTIP 2025. Thus, the Board of Directors considers that there is no need to issue new class C shares.
Following conversion of the relevant number of Treasury Shares to ordinary shares, the ordinary shares are intended to be both transferred to LTIP 2025 participants as well as sold in the market in order to cover the cash-flow related to social contribution costs associated with LTIP 2025. For this purpose, the Board of Directors proposes that the Annual General Meeting resolves to transfer not more than 366,000 ordinary shares free of charge to participants in accordance with LTIP 2025 and that not more than 95,160 ordinary shares may be sold to cover social contribution costs arising as a result of LTIP 2025.

Scope and costs for LTIP 2025
LTIP 2025 will be reported in accordance with IFRS 2, which means that the Share Rights will be expensed as personnel costs over the Vesting Period. The costs for LTIP 2025 is estimated to amount to a maximum of approximately SEK 32.4 million, excluding social contributions, accounted in accordance with IFRS 2 based on the following assumptions: (i) that 366,000 Share Rights are allotted, (ii) that the share price, at the beginning of LTIP 2025, is SEK 106.0 per ordinary share, and (iii) that the performance conditions are fully met. Based on the same assumption as above, and subject to social contributions of approximately 26 per cent and a share price increase of 33.1 per cent from the start of LTIP 2025 until the participants are allotted shares, the costs for social contribution costs are estimated to amount to SEK 13.4 million. The total cost for LTIP 2025, including costs according to IFRS 2, is therefore estimated to a maximum of SEK 15.3 million per year.

Dilution and effects on key ratios
Upon maximum allotment of Share Rights 366,000 ordinary shares will be allotted to participants under LTIP 2025, and that 95,160 ordinary shares will be used to secure social contributions arising as a result of LTIP 2025 which would entail a dilution effect of approximately 0.58 per cent of the total number of ordinary shares in the company.
Given the above assumptions regarding scope and costs, and that LTIP 2025 was introduced in 2023 instead, it is estimated that the key figure earnings per share for full year 2024 would have decreased from SEK 3.55 to approximately SEK 3.36.
If also the LTIP 2022 and 2024 are included in the calculation, the maximum dilution effect would amount to approximately 1.10 percent of the ordinary shares in the company, as of the date of this notice.

Decision to transfer own ordinary shares
The Board of Directors proposes that the Annual General Meeting resolves that class C shares, may, following the re-classification of the relevant number of Treasury Shares into ordinary shares, be transferred free of charge to participants of LTIP 2025 in accordance with the adopted terms and conditions in order to secure possible social contributions arising as a result of LTIP 2025.
The Board of Directors therefore proposes that the Annual General Meeting resolves that not more than 366,000 ordinary shares may be transferred to participants in accordance with the terms and conditions of LTIP 2025 and that not more than 95,160 ordinary shares shall be transferred on Nasdaq Stockholm, including through a financial intermediary, at a price within the registered price range at the relevant time, to cover any social contributions in accordance with the terms and conditions of LTIP 2025. The number of shares to be transferred is subject to re-calculation in the event of a bonus issue, split, rights issue and/or other similar events.

The background and rationale for the proposal
The purpose of LTIP 2025 is to create conditions for motivating and retaining competent employees within the Biotage group and to increase the coherence between the employees’, shareholders’ and the company’s objectives, as well as to increase the motivation to reach and exceed the company’s financial targets. LTIP 2025 has been designed so that the programme includes both current and future senior executives and other key employees.
By offering Share Rights that are based on both share price development and partly on strategic goals, the participants are premiered for increased shareholder value/value-creating measures. LTIP 2025 also rewards employees’ continued loyalty and thus the long-term value growth of the company. After these considerations, the Board of Directors considers that LTIP 2025 will have a positive effect on the future development of the Biotage group and will consequently be beneficial for both the company and its shareholders.

The preparation of the proposal
LTIP 2025 has been prepared by the company’s Board of Directors and its Remuneration Committee in consultation with external advisors. LTIP 2025 has been discussed by the Board of Directors at meetings held in February and March 2025.
Item 19 – Resolution on authorization for the Board of Directors to issue shares
Item 19a – Main proposal
The Board of Directors proposes that the Annual General Meeting adopts a resolution to authorize the Board of Directors to, until the Annual General Meeting to be held in 2026, at one or several occasions and with or without deviation from the shareholders’ pre-emption rights, adopt resolutions to issue ordinary shares. The Board of Directors shall have the right to resolve that the shares shall be paid in cash or be paid in kind or otherwise be subject to conditions referred to in Chapter 2, Section 5, second paragraph 1-3 and 5 of the Swedish Companies Act or that the shares shall be subscribed for with a right of set-off. The shareholders shall retain their preferential rights if the Board of Directors resolves to issue new shares against cash contribution. The number of ordinary shares issued may not correspond to a dilution of more than 15 percent of the total number of ordinary shares outstanding before the first exercise of the proposed authorization, after full exercise of the hereby proposed authorization.
Notwithstanding what is stated above regarding preferential rights for existing shareholders in case of an issue of shares against cash contribution, directed issues may be made in order to finance acquisitions of companies or parts of companies. In case of a directed cash issue of shares, such issue shall be made at market terms and conditions. Considering the above, the Board of Directors shall also be authorized to resolve on such other conditions that the Board of Directors finds necessary to carry out the issues. The reasons for the right to deviate from the shareholders’ preferential rights are to enable the company to, in a quick and effective way, finance acquisitions of companies or parts of companies.
The Board of Directors, or any person appointed by the Board of Directors, shall be authorized to make minor adjustments of the resolution adopted by the Annual General Meeting in order to fulfil the registration with the Swedish Companies Registration Office (Sw. Bolagsverket).
Item 19b – Alternative proposal
If the proposal in item 19a above does not get the required supportive votes from the Annual General Meeting to be passed, the Board of Directors proposes that it is given an authorization to issue new ordinary shares corresponding to a dilution of not more than 10 percent, on the same terms and conditions as stated above in item 19a.
_____________________

Majority requirements
A decision according to the proposal pursuant to item 19 above are valid only when supported by shareholders holding not less than two-thirds (2/3) of both the votes cast and of the shares represented at the Annual General Meeting. A decision according to the proposal pursuant to item 18 above is valid only when supported by shareholders holding not less than nine-tenths (9/10) of both the votes cast and of the shares represented at the Annual General Meeting.

Processing of personal data
For information on how your personal data is processed, see the integrity policy that is available at Euroclear’s webpage, www.euroclear.com/dam/ESw/Legal/Privacy-notice-bolagsstammor-engelska.pdf. If you have questions regarding our processing of your personal data, you can contact us by emailing info@biotage.com.

Documents
The accounting documents, the auditor’s report, the remuneration report and complete proposal for the resolution under item 18 above together with the auditor’s report in accordance with Chapter 8, Section 54 of the Swedish Companies Act and the Board of Directors’ statement in accordance with Chapter 18, Section 4 will be made available at the company at the address Vimpelgatan 5 in Uppsala, Sweden, no later than three weeks prior to the Annual General Meeting. In addition, the reasoned opinion from the Nomination Committee will be available at the company’s address stated above no later than four weeks prior to the Annual General Meeting. The above documents will also be sent to all shareholders that intend to attend the Annual General Meeting and all other shareholders upon request and will also be available on the company’s website, www.biotage.com.

This is an in-house translation of the Swedish original version. In case of any discrepancies between the English language version and the Swedish language version, the Swedish language version shall prevail.
_____________________
Uppsala in March 2025
Biotage AB (publ)
The Board of Directors

[1] The average adjusted EBITDA-margin is measured as an average over FY 2025, FY 2026 and FY 2027 before deduction of costs for long-term incentive programs.
[2] Biotage’s CO2 footprint generated from the use of virgin polypropylene in instrument related parts such as covers, internal parts and accessories.